HOW DO BACTERIA INACTIVATE DRUGS
BACTERIAL
ENZYMES
Some bacteria become resistant by producing enzymes that destroy antibiotics. These enzymes break down the drug before it can act, making treatment ineffective.
THE ILLUME ANGLE
At Illume, we let antibiotics themselves answer the only question that matters:
will it work??
We re-engineer real antibiotics into smart molecular probes.
When bacteria interact with the probe, the enzyme either breaks it down or leave it intact. That interaction releases a built-in DNA signal we can quickly detect.
By observing whether the probe is broken down or remains intact, we can directly determine whether an antibiotic will be effective against the bacteria.
THE RESULTS AND READOUT
Probe breakdown triggers a fluorescent signal that reveals active resistance in real time, allowing clinicians to quickly determine whether an antibiotic will work for the patient.
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Our goal is to recreate what actually happens inside the patient’s body, but inside a test tube.
By exposing the patient’s own bacteria to antibiotics in our vials, we can see how the bacteria truly respond, giving a clear and accurate answer on what will work.
we save up on
TIME
and
COST
of diagnosis
